首页> 外国专利> Crystalline forms of compound {5 - Chloro - 5 - methyl - 4 - oxo - 3 - 4 - ((4 - ((trifluoromethyl) oxy phenyl - 1,4 - dihydro - 2-pyridinyl methyl dihydrogen phosphate and Method for preparing them, and their salts, Pharmaceutical compositions containing them and Use thereof for the Treatment of malaria

Crystalline forms of compound {5 - Chloro - 5 - methyl - 4 - oxo - 3 - 4 - ((4 - ((trifluoromethyl) oxy phenyl - 1,4 - dihydro - 2-pyridinyl methyl dihydrogen phosphate and Method for preparing them, and their salts, Pharmaceutical compositions containing them and Use thereof for the Treatment of malaria

机译:化合物{5-氯-5-甲基-4-氧代-3-[4-((4--((三氟甲基)氧基]苯基]-1,4-二氢-2-吡啶基])磷酸二氢甲酯的结晶形式和方法用于制备它们及其盐,包含它们的药物组合物及其在治疗疟疾中的用途

摘要

Claim 1: a compound of the formula (1) or a Salt thereof. Claim 2: The Compound according to claim 1, which is in the form of the free acid. Claim 3: a Salt of the compound according to claim 1, which is a tromethamine Salt, a Salt of sodium or potassium salt.Claim 3: a Crystalline Solid Compound or Salt thereof according to any one of claims 1 to 3.
机译:1.权利要求1的化合物或其盐。权利要求2:根据权利要求1的化合物,其为游离酸的形式。权利要求3:根据权利要求1的化合物的盐,其是三甲胺盐,钠盐或钾盐。权利要求3:根据权利要求1至3中任一项的结晶固体化合物或其盐。

著录项

  • 公开/公告号AR075522A1

    专利类型

  • 公开/公告日2011-04-06

    原文格式PDF

  • 申请/专利权人 GLAXO GROUP LIMITED;

    申请/专利号AR2010P100486

  • 发明设计人

    申请日2010-02-18

  • 分类号C07F9/09;C07D213/68;C07D213/61;A61K31/661;A61K31/4418;A61K31/4412;A61P33/06;

  • 国家 AR

  • 入库时间 2022-08-21 18:07:29

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