substantially spherical microsphere, injectable composition, and use of the microsphere or composition

摘要

SUBSTANTIALLY SPHERIC MICROSPHERE, INJECTABLE COMPOSITION, AND, USE OF MICROSPHERE OR COMPOSITION. The present invention relates to compositions and methods for treating diseases and disorders, including cancer and various other angiogenesis dependent diseases, vascular dysfunctions, arteriovenous malformations (AVM), hemorrhagic processes and treatment of pain, in particular tumor-related pain, by drug administration and / or therapeutic embolization using microspheres. More particularly, the invention relates to non-ionic contrast agents containing microspheres, compositions comprising such microspheres, as well as methods for preparing and using such compositions for embolization therapy. The invention further relates to compositions and methods using detectable microspheres for administration of targeted medicament, regardless of whether embolization is also required.