combination of glycoisoforms for the treatment or prevention of septicemia, erythropoietin glycoform-producing transgenic cell line, pharmaceutical composition including such combination, procedures for obtaining the cell line, procedures for producing such a combination of glycoisoforms and methods for treatment and prevention of septicemia

摘要

COMBINATION OF GLYCOISOFORMS FOR THE TREATMENT OR PREVENTION OF SEPTICEMIA, TRANSGENIC CELL LINE PRODUCING ERYTHROPOIETIN GLYCHOFORMS, PHARMACEUTICAL COMPOSITION OF INCLUDING SUCH COMBINATION, PROCEDURES FOR GETTING PROTECTION, LINING , a combination of erythropoietin glycoisoforms, where such glycoisoforms can include an amount of sialic acid ranging from 4 to 10 molecules of sialic acid per molecule of erythropoietin, the combination of glycoisoforms can be used for the treatment or prevention of septicemia, a pharmaceutical composition including such a combination, a cell line producing a combination of erythropoietin glycoisoforms, procedures for obtaining the cell line, procedure for producing such a combination of glycoisoforms and methods of treatment and prevention of septicemia.