pyridyl and pyridimil substituted pyrrol, thiophene and furan derivatives as kinase inhibitors

摘要

B PIRROL, THIOPHENE AND FURAN DERIVATIVES REPLACED BY PYRIDIL AND PYRIDIMIL AS KINASE INHIBITORS D The present invention relates to the compounds of formula (1) below, or the pharmaceutically acceptable salts thereof, where G, W, R ~ 2 ~, R ~ 3 ~, R ~ 4 ~, R ~ 5 ~ and R ~ 6 ~ are as defined in the specification. The invention also relates to processes and intermediates for the preparation of the compounds of formula (1), pharmaceutical compositions comprising these and methods for treating cell proliferative disorders. The compounds of the formula (1) are useful, in therapy, in the treatment of diseases associated with unregulated protein kinase activity, such as cancer.