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Treatment of diseases and disorders using Colony forming cells cultured and expanded in vitro self-renewal

机译:使用培养和扩增的体外自我更新的集落形成细胞治疗疾病和失调

摘要

1. A therapeutically effective quantitative management method for an organ, tissue or subject from a biological component or component, including a group of individual somatic cells (cf-sc) separated from the bone marrow to form spontaneous cells,wherein said CF-SC does not have multipotent differentiation capacity, where said CF-SC has a normal karyotype, where said CF-SC are not immortalized, where said CF-SC expresses CD13, CD44, CD49c, CD90, HLA Class-1 and ß (beta) 2-,Here, cf-sc does not represent CD10, CD34, CD45, CD62L, or CD106. 2. The management of therapeutic quantities of a biological component or component to an organ, tissue or body; It includes: (a) separation of biological components or components separated from bone marrow to form somatic cells from isolated colonies, (b) management of such biological components or components to such organs, tissues or bodies, In this case, cf-sc does not have much difference ability. In this case, cf-sc has a normal cavity, and this kind of cf-sc will not live forever,wherein said CF-SC expresses Microglobulin CD13, CD44, CD49c, CD90, HLA Class-1 and ß (beta) 2, and where said CF-SC does not express CD10, CD34, CD45, CD62L, or CD106.
机译:1.一种用于治疗器官,组织或受试者的生物成分的治疗有效定量管理方法,所述方法包括从骨髓分离形成自发细胞的一组个体体细胞(cf-sc),其中所述CF-SC不具有多能分化能力,其中所述CF-SC具有正常核型,其中所述CF-SC没有被永生化,其中所述CF-SC表达CD13,CD44,CD49c,CD90,HLA 1类和ß(β)2在此,cf-sc不代表CD10,CD34,CD45,CD62L或CD106。 2.管理器官,组织或身体的生物成分或多种成分的治疗量;它包括:(a)从分离的菌落中分离出生物学成分或与骨髓分离的成分,以形成体细胞;(b)将此类生物学成分或成分管理到这些器官,组织或身体,在这种情况下,cf-sc没有太大的区别能力。在这种情况下,cf-sc具有正常的腔,这种cf-sc不会永远存在,其中CF-SC表示微球蛋白CD13,CD44,CD49c,CD90,HLA Class-1和ß(β)2并且其中所述CF-SC不表达CD10,CD34,CD45,CD62L或CD106。

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