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divalent metalion - loaded nano - transport system with dendritisk architecture suitable for therapy
divalent metalion - loaded nano - transport system with dendritisk architecture suitable for therapy
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机译:具有树枝状结构的二价金属离子负载纳米传输系统,适用于治疗
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摘要
Described is the use of a nanocarrier having a dendritic structure which is composed of a dendritic core and at least one shell for the non-covalent encapsulation and/or transport of divalent metal-ions, preferably Cu-ions or Zn(II)-ions. Also described is a pharmaceutical composition containing such nanocarrier complexed divalent metal-ions in a non-covalent encapsulated form. Finally several therapeutic uses of such a nanocarrier divalent metal-ion complex are described, for example for slowing down ageing or for the treatment of Cu-ion transport disorders like Alzheimer's disease (AD) or Menkes disease.
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