the invention provides compositions and methods for the treatment of cell u043fu0440u043eu043bu0438u0444u0435u0440u0430u0442u0438u0432u043du043eu0433u043e violations using the agonist and one or more u0440u0435u0446u0435u043fu0442u043eu0440u0430 u04302u0430 PDE inhibitors.methods and compositions may also include the use of u0430u043du0442u0438u043fu0440u043eu043bu0438u0444u0435u0440u0430u0442u0438u0432u043du043eu0433u043e compounds.
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