NOVEL ERYTHROMYCIN DERIVATIVES, METHOD FOR THEIR PREPARATION, THEIR NOVEL AMINE INTERMEDIATES AND PHARMACEUTICALS CONTAINING THE SAID ERYTHROMYCIN DERIVATES

摘要

Erythromycin derivs. of formula (I) and their acid addn. salts, are new. R = -(CH2)nAr; n = 3 - 5; Ar = heterocyclic gp. (opt. substd. one or more times) (37 gps shown in specification); or R = a gp. (i); Z = H or an acid residue. Ar can also be a gp. (a)-(e) (opt. substd.); R can also be a gp. (ii) or (iii); (opt. substd.). Also claimed are amines RNH2 (III) and their acid addn. salts.