COMPOSITION COMPRISING A PRO364 OR PRO175 POLYPEPTIDE IN ADMIXTURE WITH A PHARMACEUTICALLY ACCEPTABLE CARRIER AND CARDIOVASCULAR, ENDOTHELIAL OR ANGIOGENIC AGENT, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND THEIR USE FOR PREPARING MEDICAMENTS

摘要

Compositions and methods are disclosed for stimulating or inhibiting angiogenesis and/or cardiovascularization in mammals, including humans. Pharmaceutical compositions are based on polypeptides or antagonists thereto that have been identified for one or more of these uses. Disorders that can be diagnosed, prevented, or treated by the compositions herein include trauma such as wounds, various cancers, and disorders of the vessels including atherosclerosis and cardiac hypertrophy.