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METHOD FOR PREPARING VESICLES LOADED WITH BIOLOGICAL MATERIAL, THEIR USES AND A COMBINATION OF PHARMACEUTICAL COMPOSITIONS FOR PREPARING SUCH VESICLES

机译:载有生物材料的囊泡的制备方法,其用途以及制备这类囊泡的药物组合物的组合

摘要

The present invention discloses a method for an efficient entrapment of active biological material in liposomes. The method is based on the steps of drying a suspension of liposome-forming lipids and then hydrating the dry composition obtained with an aqueous solution containing a biologically active material to be entrapped in high yield in the liposomes thus formed. The invention also concerns liposomal formulations produced by the method of the invention and their uses.
机译:本发明公开了一种有效地将活性生物材料截留在脂质体内的方法。该方法基于以下步骤:干燥形成脂质体的脂质的悬浮液,然后用含有生物活性材料的水溶液水合获得的干燥组合物,该水溶液被高产率地截留在如此形成的脂质体中。本发明还涉及通过本发明的方法生产的脂质体制剂及其用途。

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