首页> 外国专利> POPULATION BASED ASSESSMENTS AND MEANS TO RANK THE RELATIVE IMMUNOGENICITY OF PROTEINS

POPULATION BASED ASSESSMENTS AND MEANS TO RANK THE RELATIVE IMMUNOGENICITY OF PROTEINS

机译:基于人群的评估和手段,使蛋白质具有相对的免疫原性

摘要

The present invention provides means to assess immune response profiles of populations. In particular, the present invention provides means to qualitatively assess the immune response of human populations wherein the immune response directed against any protein of interest is analyzed. The present invention further provides means to rank proteins based on their relative immunogenicity. In addition, the present invention provides means to create proteins with reduced immunogenicity for use in various applications.
机译:本发明提供了评估人群的免疫应答特征的方法。特别地,本发明提供了定性评估人的免疫应答的手段,其中分析了针对任何目的蛋白质的免疫应答。本发明进一步提供了基于蛋白质的相对免疫原性对蛋白质进行分级的方法。另外,本发明提供了产生具有降低的免疫原性的蛋白质以用于各种应用的手段。

著录项

  • 公开/公告号IL163139B

    专利类型

  • 公开/公告日2010-12-30

    原文格式PDF

  • 申请/专利权人 GENENCOR INTERNATIONAL INC.;

    申请/专利号IL163139

  • 发明设计人

    申请日2004-07-22

  • 分类号G01N33/53;C12N9/56;C12Q1/02;G01N33/50;G01N33/566;G01N33/567;

  • 国家 IL

  • 入库时间 2022-08-21 18:06:30

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