PHARMACEUTICAL FORMULATIONS COMPRISING (A) LEVOTHYROXINE SODIUM, (B) MICRO CRYSTALLINE CELLULOSE, AND (C) PREGELATINISED STARCH, USE THEREOF IN THE MANUFACTURE OF MEDICAMENTS FOR THE TREATMENT OF THYROID HORMONE DISORDERS IN A MAMMAL AND A PROCESS FOR PREPARING SAID PHARMACEUTICAL FORMULATIONS

摘要

There is provided a stable pharmaceutical formulation comprising (a) an effective amount of levothyroxine sodium, (b) microcrystalline cellulose which has a mean particle size of less than 125 m and is present in an amount of 60 to 85% w/w based upon the total weight of the formulation, and (c) pregelatinised starch present in an amount of 5 to 30% w/w based upon total weight of the formulation. There is also provided a process for the preparation of such a formulation.