首页> 外国专利> REJUVENATING CORONARY ARTERY BY IMPROVING BLOOD FLOW WITH THE HELP OF INSERTION OF NANO-BALLS (ENCAPSULATED NANOPARTICLES) CONTAINING THERAPEUTIC AGENTS BY NON-IMPLANTABLE DEVICE FOR TISSUES AND THEREBY PROVIDING IN TISSUE RELEASE TO ADDRESS THE REQUIRED CELL CYCLE

REJUVENATING CORONARY ARTERY BY IMPROVING BLOOD FLOW WITH THE HELP OF INSERTION OF NANO-BALLS (ENCAPSULATED NANOPARTICLES) CONTAINING THERAPEUTIC AGENTS BY NON-IMPLANTABLE DEVICE FOR TISSUES AND THEREBY PROVIDING IN TISSUE RELEASE TO ADDRESS THE REQUIRED CELL CYCLE

机译:通过使用非植入性组织治疗装置来改善血液流动并通过插入包含治疗剂的纳米球(胶囊化纳米颗粒)来改善血液流动,并提供解决方案以解决上述问题

摘要

The invention discloses a Drug Releasing Insertable Device (DRID) with one or more surfaces of the DRID. The one or more surface of the DRID includes one or more, but not limited to, one or more hydrophilic surfaces, and one or more non-hydrophilic surfaces. The one or more surfaces of the DRID are coated with nano-encapsulated particles, The nano-encapsulated particles include one or more excipients that have one or more properties of, stabilizing the nano-encapsulated particles, affinity for tissues of a target site, and promoting healing of a target site. The drug releasing insertable device has a porous bed on the one or more non-hydrophilic surfaces such that, the nano-encapsulated particles are deposited in one or more pores of the porous bed. The nano-encapsulated particles are released from the surface upon coming in a close proximity of the target site or upon change in pH. The invention also discloses a method for preparing the drug releasing insertable device.
机译:本发明公开了一种具有一个或多个DRID表面的药物释放可插入装置(DRID)。 DRID的一个或多个表面包括一个或多个但不限于一个或多个亲水性表面和一个或多个非亲水性表面。 DRID的一个或多个表面涂覆有纳米囊封的颗粒。纳米囊封的颗粒包括一种或多种赋形剂,其具有以下一种或多种性质:稳定纳米囊封的颗粒,对靶部位的组织的亲和性;以及促进目标部位的愈合。药物释放可插入装置在一个或多个非亲水性表面上具有多孔床,使得纳米囊封的颗粒沉积在多孔床的一个或多个孔中。纳米封装的颗粒在紧靠目标部位或pH值变化时从表面释放。本发明还公开了一种制备药物释放可插入装置的方法。

著录项

  • 公开/公告号IN2009MU01337A

    专利类型

  • 公开/公告日2010-12-10

    原文格式PDF

  • 申请/专利权人

    申请/专利号IN1337/MUM/2009

  • 申请日2009-06-02

  • 分类号A61P9/10;A61M25/04;A61L29/00;A61K47/34;A61F2/84;A61K9/51;B82B1/00;A61L31/00;B82Y5/00;A61M25/10;A61K31/337;A61M29/00;A61K47/14;A61K31/436;A61M29/02;A61L29/16;A61K47/24;A61P9/00;B05D7/00;B05D5/00;A61B5/452;A61F2/82;A61M31/00;

  • 国家 IN

  • 入库时间 2022-08-21 18:05:53

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