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METHOD FOR MANUFACTURING A PHARMACEUTICAL COMPOSITION AS SOLID DOSAGE FORM COMPRISING DESMOPRESSIN ACETATE AS A THERAPEUTICALLY ACTIVE AGENT
METHOD FOR MANUFACTURING A PHARMACEUTICAL COMPOSITION AS SOLID DOSAGE FORM COMPRISING DESMOPRESSIN ACETATE AS A THERAPEUTICALLY ACTIVE AGENT
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机译:制备包含醋酸去氨加压素作为治疗活性剂的固体剂型的药物组合物的方法
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摘要
The present invention relates to a novel pharmaceutical composition as a solid dosage form comprising desmopressin as a therapeutically active ingredient, and to a method for manufacturing thereof. The invention relates to a pharmaceutical composition as a solid dosage form comprising desmopressin, or a pharmaceutically acceptable salt thereof, as a therapeutically active ingredient together with a pharmaceutically acceptable excipient, diluent or carrier, or mixture thereof, wherein at least one of said excipient, diluent and carrier is a substance selected from a monosaccharide, disaccharide, oligosaccharide and a polysaccharide, wherein the said substance has an average particle size in the range of from 60 to 1 000 µm. A method according to the present invention provides an improved production of solid dosage forms of desmopressin.
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