Crystalline hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl-8-azabicyclo3.2.1oct-3-yl}amide

摘要

Disclosed is a crystalline salt form which is the hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide or a solvate thereof. Also disclosed is the use of a crystalline salt form as defined above for manufacture of a medicament for the treatment of a medical condition in a mammal associated with 5-HT4 receptor activity (including disorders of reduced motility of the gastrointestinal tract, chronic constipation, constipation-predominant irritable bowel syndrome, diabetic and idiopathic gastroparesis, and functional dyspepsia).