Pure pharmacological synthesis of amlodipina and losartan with enhanced stability

摘要

The utility model relates to a pharmacological component, which comprises: (a) the particle form of ammonium carbamate; (b) the particle form of garnet; (c) a stabilizer, which is an antioxidant selected from butadiene hydroxytoluene, butadiene hydroxyhydrazine and Fumin, This includes a quantity of 0.005-5% by weight based on the total weight of the composition. This component is characterized by the ratio of amlodipina: Losartan in the range of 1:1 to 1:40, which is very useful in the treatment of angioplasty, hypertension, vascular thrombosis, etc.