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Pyridine (1,2-a) pyridine derivatives as mirex inhibitors

机译:吡啶(1,2-a)吡啶衍生物作为灭蚁灵抑制剂

摘要

It refers to the compounds derived from pyridinic acid [1,2-a] pyridine (I), wherein RA is the heterogeneous of H, halogeno, arilo (C6-C12) or 5-12 members; Rb is h, rc-scorc, and, among others, RC is asphalt (C1-C6),Cyclopropyl (C3-C10),Arilo and others [1 - [1 - [6 - [6 - [6 - [6 - [6 - [6 - [4-fluoro] sulfur] benzene] 1]]]] 1.3-benzodiazepine-2-il-cyclopropane amide, etc. He also mentioned a preparatory process and a pharmacology composer. These compounds inhibit the protein quinasa met, which is useful in the treatment of vascular diffusion disorders, fibrosis disorders, allergies, asthma.
机译:它是指衍生自吡啶酸[1,2-a]吡啶(I)的化合物,其中RA是H,卤代,芳基(C6-C12)或5-12位成员的异源基团; Rb是h,rc-scorc,并且其中RC是沥青(C1-C6),环丙基(C3-C10),阿里洛和其他[1-[1-[6-[6-[6-[6- [6- [6- [4- [4-氟]硫]苯] [1]]]] 1.3-苯并二氮杂-2-il-环丙烷酰胺等。他还提到了制备方法和药理学作曲家。这些化合物抑制了quinasa met蛋白,可用于治疗血管扩散疾病,纤维化疾病,过敏,哮喘。

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