NEW PROCEDURES FOR FORMULATION OF PREPARATION FOR LOCAL ANALGESIA IN DENTISTRY

摘要

Invention herewith described refers to the new procedures for formulation of the preparation for local analgesia in dentistry that is suitable for treatment of alveolitis after dental surgery such as a tooth extraction (I) contains lidocaine (2 - (diethyl amino)-n-(2.6-dimethylphenyl) acetamide) of the formula (I),Or procaine (2-(diethyl amino)ethyl 4-aminobenzoate) of the formula (II)Formulated in solvent consisting of ethanol of the formula (III),CH3CH2OHDiethyl ether of the formula (IV)CH3CH2O CH2 CH3Iodoform of the formula (V)CHJ3and glycerol of the formula (VI)H2C-OHHC-OHH2C-OHAt the temperature of 20º C to 35º C, molar ratio analgesic lidocaine, iodine, glycerol, diethyl ether, ethanol 1.0:2.0:28.4:74.4:62.8 and analgesic procaine, iodine, glycerol, diethyl ether, ethyl alcohol 1.0:2.0:25.7:67.3:108.5 and the formulation time of 1.0 hour.