THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASE COMPRISING 2-AMINO-1,3-PROPANEDIOL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE

摘要

ABSTRACTTHERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASE COMPRISING 2-AMINO-1, 3-PROPANEDIOL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR TREATMENT OF INFLAMMATORY BOWEL DISEASEA novel therapeutic and prophylactic agent for inflammatory bowel diseases and a method for treating inflammatory bowel diseases.The agent comprises a 2-amino-1,3-propanediol derivative(e.g.,2-amino-2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl-1,3- propanediol hydrochloride) represented by the chemical formula (1) or a pharmaceutically acceptable salt or hydrate thereof: (Chemical formula 1) The agent is useful in the treatment or prevention of Crohn' s disease, Crohn's disease in large intestine, intestinal Behcet's disease, ulcerative colitis, bleeding rectal ulcer and pouchitis.[No Figures]