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Diagnostic test panel for the diagnostic of malaria and severe bacterial infections.
Diagnostic test panel for the diagnostic of malaria and severe bacterial infections.
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机译:诊断测试小组,用于诊断疟疾和严重细菌感染。
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摘要
A test panel and kit, in package form, is for use in the diagnosis of malaria and severe bacterial infection in a test sample. They include monoclonal antibodies to histidine-rich protein H5 to P. falciparum aldolase and/or pan Pfalciparum lactate dehydrogenase, to Angiopoietin-1 and/or Angiopoietin-2, and to C-reactive protein and/or procalcitonin. A rapid diagnostic test device includes a portion to receive the panel, a chamber to receive the sample for contact with the monoclonal antibodies, and an element for detecting signals from the sample in contact with the monoclonal antibodies. Processors analyze the signals to differentiate between P.falciparum malaria likely or unlikely at risk for severe/cerebral malaria, non-P falciparum malaria, and infection which is likely or unlikely to be severe bacterial infection, in the sample. Also disclosed are an associated method and a computer readable medium which stores instructions for operating the test device.
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