peptide able to disassemble the protein complexes between the p53 protein changed his 273 and the protein of oncosoppressiva in cancer cells and its uses in the medical field.

摘要

The present invention concerns a SIMP peptide (Short-interfering mutant p53 peptides) suitable to disrupt the protein complexes within tumour cells resulting from m-p53 and p73 proteins selectively in tumours wherein m-p53 contains His273 mutation.