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New derivatives chromen-2-one and their use as inhibitors of reuptake of monoamine neurotransmitters.
New derivatives chromen-2-one and their use as inhibitors of reuptake of monoamine neurotransmitters.
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机译:新的衍生物chromen-2-one及其作为单胺神经递质再摄取抑制剂。
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摘要
A compound of formula 1: Formula ** ** or any of its stereoisomers or any mixture of its stereoisomers, or a pharmaceutically acceptable salt thereof, wherein Q represents a chromen-2-one-yl group; Group chromen-2-one-yl which is substituted with a heteroaryl group; heteroaryl group is optionally substituted by one or more substituents independently selected from the group consisting of halo, trifluoromethyl, triflúormetóxido, cyano, amino, nitro, hydroxide, alkoxide, cycloalkoxy, metilenodióxido, alcílico of etilenodióxido, cicloalcílico, cicloalcilalcílico, alkenyl and alkynyl ; Group chromen-2-one-yl which may be substituted, optionally, with one or more substituents selected from the group consisting of: halo, trifluoromethyl, triflúormetóxido, cyano, amino, nitro, hydroxide, alkoxide, cycloalkoxy, metilenodióxido, -alkyl of etilenodióxido, -cycloalkyl, cicloalcilalcilo, alkenyl and alkynyl; R1 represents hydrogen or -alkyl -alkyl which may be substituted, optionally, with one or more substituents selected from the group consisting of: halo, trifluoromethyl, triflúormetóxido, cyano, amino, nitro, hydroxide, alkoxide, cycloalkoxy, metilenodióxido, -alkyl of etilenodióxido, -cycloalkyl, cicloalcilalcilo, alkenyl and alkynyl;
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