solid pharmaceutical composition based famotidine against gastric hypersecretion and related diseases, more synergistic efficacy and faster performance.

摘要

solid pharmaceutical composition based famotidine against gastric hypersecretion and related diseases, more synergistic efficacy and faster performance.; solid pharmaceutical composition against gastric hypersecretion and related diseases, based on famotidine or other active ingredient antacid, and a set excipient consisting of an alkalizing value added, preferably trisodium citrate dihydrate, a disintegrant and a number of additional pharmaceutically acceptable ingredients, in which these components are present uniformly dispersed as a conglomerate of compressed powder or granulate to a particle size and concentrations that ensure a rapid disintegration of the drug in the mouth or in a liquid, even in less than 60 seconds. This composition is usable for the preparation of anti-ulcer drug famotidine tablets or self-dispersible granules, more synergistic effective result of the better absorption of the active ingredient by action of ingredient indicated alkalizing and faster acting, due to the high speed decomposition achieved in that format.