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NEW BETAMIMETICS OF PROLONGED ACTION FOR THE TREATMENT OF DISEASES OF THE RESPIRATORY ROUTES.
NEW BETAMIMETICS OF PROLONGED ACTION FOR THE TREATMENT OF DISEASES OF THE RESPIRATORY ROUTES.
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机译:治疗呼吸道疾病的长期有效的新行为学。
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摘要
A means a bivalent moiety chosen from the group consisting of -CR 4 R 5 -O-, -CH = CH- and -CH2-CH2-, preferably -CR 4 R 5 -O-; R 1 means -C 1-4 alkyl; R 2 and R 3 are the same or different and mean H, C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl, C 3-6 cycloalkyl, C 1-4 haloalkyl, -O-C 1-4 haloalkyl, halogen, OH, CN, NO2, C2-4-OH alkyl, -O-C1-4 alkyl, COOH or COO-C1-4 alkyl, or R 2 and R 3 together form a bivalent moiety selected from -O-CR 4 R 5 -O -, -O-CR 4 R 5 -NR 6 and -CH = CH-CH = CH-; R 4 means H or C 1-4 alkyl; R 5 means H or C 1-4 alkyl; R 6 means H or C 1-4 alkyl, optionally in the form of individual enantiomers, of mixtures of the individual enantiomers or of racemates, optionally in the form of their pharmaceutically safe acid addition salts, as well as optionally in the form of their solvates and / or hydrates
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机译:A是指选自-CR 4 R 5 -O-,-CH = CH-和-CH2-CH2-,优选-CR 4 R 5 -O-的二价部分; R 1表示-C 1-4烷基; R 2和R 3相同或不同,表示H,C 1-4烷基,C 2-4烯基,C 2-4炔基,C 3-6环烷基,C 1-4卤代烷基,-OC 1-4卤代烷基,卤素,OH,CN,NO 2,C2-4-OH烷基,-O-C1-4烷基,COOH或COO-C1-4烷基,或R 2和R 3一起形成选自-O-CR的二价部分4 R 5 -O-,-O-CR 4 R 5 -NR 6和-CH = CH-CH = CH-; R 4表示H或C 1-4烷基; R 5表示H或C 1-4烷基; R 6表示H或C 1-4烷基,任选地以单独对映体的形式,单独的对映体或外消旋物的混合物,任选地以其药学上安全的酸加成盐的形式以及任选地以其形式溶剂化物和/或水合物
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