Vaccine for treating celiac disease and method for vaccine production, using a peptide sequence conjugated to a bacterial toxin for activating the immune system against prolamines and peptide design.

摘要

Vaccine for use in the treatment of celiac disease, which contains as an effective component at least one unbranched toxic peptide sequence conjugated to a part of a bacterial toxin gliadin being the unbranched toxic peptide sequence Pro Gly Glu Glu Glu Pro Phe Pro Pro Glu Glu Pro Tyr Pro Glu Pro Glu Pro Phe Pro of the α-gliadin and the bacterial toxin being pentamer B of cholera toxin.