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Drug formulations-lipid for targeted drug delivery to lymphoid and myeloid immune cells.

机译:药物制剂-用于将药物靶向递送至淋巴和髓样免疫细胞的脂质。

摘要

A lipid-drug comprising a drug and further comprising targeting ligands in an outer surface which specifically bind to the surface of an immune cell at least one combination of the following markers complex: CD209 and CD4; or CD209 and CD45R0 wherein said drug is an immunomodulatory agent that is active in an immune cell which is directed or he said targeting ligand and wherein said targeting ligand is a monoclonal antibody.
机译:一种脂质药物,其包含药物,并且还包括在外表面上与免疫细胞表面特异性结合的靶向配体,其至少结合以下标志物复合体的至少一种:CD209和CD4;或CD209和CD45R0,其中所述药物是在所述靶向配体或所述靶向配体的免疫细胞中有活性的免疫调节剂,并且其中所述靶向配体是单克隆抗体。

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