首页> 外国专利> USE OF GENETIC POLYMORPHISMS THAT ARE ASSOCIATED WITH THE EFFECTIVENESS OF THE TREATMENT OF AN INFLAMMATORY DISEASE.

USE OF GENETIC POLYMORPHISMS THAT ARE ASSOCIATED WITH THE EFFECTIVENESS OF THE TREATMENT OF AN INFLAMMATORY DISEASE.

机译:遗传多态性的使用与炎症性疾病治疗的有效性有关。

摘要

Use of pimecrolimus in the manufacture of a drug for the treatment of pediatric atopic dermatitis in a selected patient population, where the patient population is selected from those who have either (i) a TT genotype in a locus located -1031 of the transcription initiation site of the human TNF gene, or (ii) an AA or AC genotype in the ASN60THR LTA locus of the human LTA gene.
机译:吡美莫司在制备用于治疗选定患者人群中的小儿特应性皮炎的药物中的用途,其中患者人群选自(i)转录起始位点-1031位点具有TT基因型的患者人TNF基因的“基因”,或(ii)人LTA基因的ASN60THR LTA基因座中的AA或AC基因型。

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