OLIGOMER ARRAY WITH PNA AND/OR DNA OLIGOMERS ON A SURFACE

摘要

The invention relates to an oligomer array with PNA (Peptide Nucleic Acid)and/or DNA oligomers on a surface, said oligomers comprising oligomers of 6 to20 monomers or nucleobases each. Said monomers or nucleobases comprise atleast one sequence of the general formula DDCGDD or of the general formulaDDTGDD or of the general formula HHCGHH or of the general formula HHCAHH,wherein H represents any of the bases adenine (A), cytosine (C) or thymine (T)and D represents any of the bases adenine (A), guanine (G) or thymine (T). Thelocation of the oligomers on the surface is correlated with the sequence ofthe oligomers. The inventive oligomer arrays are used to detect cytosinemethylations in genomic DNA.