DNA MOLECULES ENCODING A GLUTAMATE-GATED CHLORIDE CHANNEL IN DROSOPHILA MELANOGASTER

摘要

The present invention relates in part to isolated nucleic acid molecules(polynucleotides) which encode Drosophila melanogaster ligand-gated ionchannel proteins. The present invention also relates to recombinant vectorsand recombinant hosts which contain a DNA fragment encoding Drosophila ligand-gated ion channel proteins, substantially purified forms of associatedDrosophila ligand-gated ion channel proteins and recombinant membranefractions comprising these proteins, associated mutant proteins, and methodsassociated with identifying compounds which modulate associated Drosophilamelanogaster ligand-gated ion channel proteins, which will be useful asinsecticides.