FXIII DETECTION FOR VERIFYING SERUM SAMPLE AND SAMPLE SIZE AND FOR DETECTING DILUTION

摘要

Analyses of serum samples for the presence and amount of either of the twosubunits of human Factor XIII protein are used as a means of eliminating asignificant source of error that arises in the testing of serum and plasma.For serum samples, a negative result of an analysis for the presence ofsubunit a is a means of verifying that a sample is indeed serum, while anegative or positive result for subunit a serves to distinguish serum(negative) from plasma (positive). A positive result for the presence ofsubunit b is a means of verifying that the sample is either serum or plasmaand not any other biological fluid. A quantitative analysis of subunit b is ameans of verifying that the sample is of the intended volume rather thanhaving been reduced in volume due to improper sampling. A quantitativeanalysis of subunit b is also a means of verifying the dilution of a sample ofeither serum or plasma.