DIAGNOSIS AND PROGNOSIS OF IDIOPATHIC INTERSTITIAL PNEUMONIA BY RS35705950 SNP IN MUC5B GENE PROMOTER

摘要

The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease.