A composition comprising an extract of tiarella polyphylla and tiarellic acid isolated therefrom having antiinflammatory, antiallergic and antiasthmatic activity

摘要

The present invention relates to a composition comprising an extract of Tiarellapolyphylla, and tiarellic acid isolated therefrom having anti-inflammatory,anti-allergic and anti-asthmatic activity. The extract of Tiarella polyphyllaand the tiarellic acid isolated therefrom shows the inhibitory effect on theLTC release in vitro test and the suppressive effect on the IgE leveland the cytokine(IL-4, IL-5 and IL- 13) production, airway hyperresponsiveness,and leukocyte infiltration in OVA-induced asthmatic mice. Therefore, it canbe used as the therapeutics or functional health food for treating and preventinginflammatory, allergic and asthmatic disease.