USE OF LEISHMANIA ANTIGENS IN A DIAGNOSTIC METHOD, VACCINE AND THERAPY FOR LEISHMANIASIS

摘要

The present invention relates to the use of different recombinant antigens obtained from Leishmania chagasi or Leishmania infantum genes in assays for identifying, detecting and quantifying specific antibodies in biological material, including serum, plasma, saliva and urine from human beings, dogs and other Leishmania vertebrate hosts. These recombinant antigens, or genes or parts of genes that encode same, can be used for diagnosing leishmaniases, both the infection and/or disease. The present invention further relates to the use of these recombinant antigens, or genes or parts of genes that encode same, or formulations containing these antigens, for the treatment and/or immunisation of human beings, dogs and other vertebrate hosts, against leishmaniases.