首页> 外国专利> PICHIA PASTORIS AS A HOST FOR THE PRODUCTION OF THE RIBOSOME-INACTIVATING PROTEIN (RIP) SAPORIN AND SAPORIN FUSION CHIMAERAS

PICHIA PASTORIS AS A HOST FOR THE PRODUCTION OF THE RIBOSOME-INACTIVATING PROTEIN (RIP) SAPORIN AND SAPORIN FUSION CHIMAERAS

机译：Pichia Pastoris作为生产核糖体灭活蛋白（RIP）SAPORIN和SAPORIN FUSION CHIMAERAS的宿主

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摘要

The present invention relates to the field of recombinant protein expression and discloses a procedure for the production of toxic chimaeric proteins endowed with ribosome-inactivating activity based on the plant toxin Saporin from Saponaria officinalis in the methylotrophic yeast Pichiapastoris.

机译：本发明涉及重组蛋白表达领域，并公开了一种基于甲基营养型酵母中Saponaria officinalis 的植物毒素Saporin生产具有核糖体失活活性的有毒Chimaeric蛋白的方法。 >毕赤酵母 番茄酱。 展开▼

著录项

公开/公告号WO2011012254A1

专利类型

公开/公告日2011-02-03

原文格式PDF

申请/专利权人 CONSIGLIO NAZIONALE DELLE RICERCHE;LOMBARDI ALESSIO;LEUKAEMIA BUSTERS;UNIVERSITA DEGLI STUDI DELLAQUILA;CERIOTTI ALDO;DELLA CRISTINA PIETRO;COLOMBATTI MARCO;FABBRINI SERENA M.;FLAVELL SOPSAMORN U.;FLAVELL DAVID J.;
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申请/专利号WO2010EP04467

发明设计人 LOMBARDI ALESSIO;CERIOTTI ALDO;DELLA CRISTINA PIETRO;COLOMBATTI MARCO;FABBRINI SERENA M.;FLAVELL SOPSAMORN U.;FLAVELL DAVID J.;
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申请日2010-07-21

分类号C12N1/16;C12N15/62;C12P21/02;C07K14/415;C07K16/28;

国家 WO

入库时间 2022-08-21 17:59:35

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1. 一种由酵母菌(Pichia pastoris)制备人体血清白蛋白的方法 [P] . 中国专利： CN1298949A . 2001-06-13

2. 用甲醇酵母（Pichia Pastoris）生产神经营养素－3（NT－3）的方法及应用 [P] . 中国专利： CN1151268C . 2004.05.26

3. PICHIA PASTORIS AS A HOST FOR THE PRODUCTION OF THE RIBOSOME-INACTIVATING PROTEIN (RIP) SAPORIN AND SAPORIN FUSION CHIMAERAS [P] . 世界知识产权组织专利： WO2011012254A8 . 2011-04-14

机译： Pichia Pastoris作为生产核糖体灭活蛋白（RIP）SAPORIN和SAPORIN FUSION CHIMAERAS的宿主

4. Pichia pastoris as a host for the production of the ribosome-inactivating protein (RIP) saporin and saporin fusion chimaeras [P] . 欧洲知识产权局专利： EP2280063A1 . 2011-02-02

机译：巴斯德毕赤酵母为宿主，用于生产核糖体失活蛋白（RIP）saporin和saporin融合嵌合体

5. Pichia pastoris as a host for the production of the ribosome-inactivating protein (RIP) saporin and saporin fusion chimaeras [P] . 欧洲知识产权局专利： EP2280063A8 . 2011-03-23

机译：巴斯德毕赤酵母为宿主，用于生产核糖体失活蛋白（RIP）saporin和saporin融合嵌合体

1. Process Control and Optimization for Heterologous Protein Production by Methylotrophic Pichia pastoris [J] . GAO Minjie, SHI Zhongping 中国化学工程学报（英文版） . 2013,第002期

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6. SLOW GROWTH RATE TRIGGERED TRANSITION TO A PSEUDOHYPHAL LIFESTYLE OF THE PROTEIN PRODUCTION HOST PICHIA PASTORIS [C] . Sonakshi De, Markus Buchetics, Corinna Rebnegger, Conference on biochemical and molecular engineering . 2019

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8. Genome secretome and glucose transport highlight unique features of the protein production host Pichia pastoris [O] . Diethard Mattanovich, Alexandra Graf, Johannes Stadlmann, 2009

9. Recombinant production of a peroxidase-protein G fusion protein in Pichia pastoris [O] . Krainer Florian Wolfgang, Darnhofer Barbara, Birner-Gruenberger Ruth, 2016

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2. Secretion and expression dynamics of a GFP-tagged mucin-type fusion protein in high cell density Pichia pastoris bioreactor cultivations [J] . Magnus Sjoblom ,Linda Lindberg ,Jan Holgersson . 生命科学与技术进展（英文） . 2012,第3期

3. Biocatalytic production of chitosan polymers from shrimp shells,using a recombinant enzyme produced by Pichia pastoris [J] . Eduardo Mere Del Aguila ,Laidson Paes Gomes ,Cristina Tristao Andrade . 美国分子生物学期刊（英文） . 2012,第4期

4. 食线虫真菌碱性蛋白酶cDNA基因的克隆及在Pichia pastoris中的异源表达 [C] . 赵明莲 ,张克勤 . 第三届会员代表大会暨全国第六届菌物学学术讨论会 . 2003

5. 一种乙肝表面抗原结合蛋白(SBP)在Pichia Pastoris中的表达,纯化工艺及功能研究 [A] . 庞云 . 2009