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Prognostic markers for prediction of treatment response and/or survival of breast cell proliferative disorder patients

机译:预测乳腺癌细胞增生性疾病患者的治疗反应和/或生存的预后标志物

摘要

The present invention relates to methods for prognosis and/or predicted outcome of treatment with estrogen treatment of breast cell proliferative disorder patients, in particular breast carcinoma. This is achieved by determining the expression level of PITX2 or the genetic or the epigenetic modifications of the genomic DNA associated with the gene PITX2. The invention also relates to sequences, oligonucleotides and antibodies which can be used within the described methods.
机译:本发明涉及用雌激素治疗乳腺细胞增生性疾病患者,特别是乳腺癌的预后和/或预测结果的方法。这可以通过确定PITX2的表达水平或与基因PITX2相关的基因组DNA的遗传或表观遗传修饰来实现。本发明还涉及可在所述方法中使用的序列,寡核苷酸和抗体。

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