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Base plate for use in mass spectrometry analysis, and method and apparatus for mass spectrometry analysis

机译:用于质谱分析的基板以及用于质谱分析的方法和装置

摘要

A base plate (3) for mass spectrometry analysis is disclosed, which is used in a method in which a substance immobilized on a surface of the base plate (3) is desorbed from the surface by application of laser light thereto and the ion of the desorbed substance is captured for mass spectrometry analysis. The base plate (3) includes, on at least a portion of the surface thereof, a roughened metal surface capable of exciting local plasmon when exposed to laser light. The roughened metal surface is formed, for example, by forming numerous micropores (6) in a surface of an alumina layer (5) and filling gold particles (8) in the micropores (6). Each gold particle (8) has a head portion having a size larger than a diameter of the micropore (6) and projecting from the surface of the alumina layer (5). Use of this base plate (3) allows use of lower-power laser light.
机译:公开了一种用于质谱分析的基板(3),该基板用于一种方法,其中固定在基板(3)的表面上的物质通过向其施加激光和离子的离子而从该表面解吸。捕获解吸的物质用于质谱分析。基板(3)在其表面的至少一部分上包括粗糙的金属表面,该金属表面在暴露于激光时能够激发局部等离子体激元。粗糙化的金属表面例如通过在氧化铝层(5)的表面上形成多个微孔(6)并在该微孔(6)中填充金粒子(8)而形成。每个金颗粒(8)具有头部,该头部的尺寸大于微孔(6)的直径并且从氧化铝层(5)的表面突出。使用该底板(3)可以使用较低功率的激光。

著录项

  • 公开/公告号EP1801567B1

    专利类型

  • 公开/公告日2011-05-04

    原文格式PDF

  • 申请/专利权人 FUJIFILM CORP;

    申请/专利号EP20060026605

  • 发明设计人 NAYA MASAYUKI;OHTSUKA HISASHI;

    申请日2006-12-21

  • 分类号G01N21/55;G01N21/65;C12Q1/68;G01N27/62;G01N30/72;

  • 国家 EP

  • 入库时间 2022-08-21 17:58:59

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