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PHARMACEUTICAL FORMULATIONS COMPRISING 9-CIS-RETINYL ESTERS IN A LIPID VEHICLE

机译：脂质车辆中包含9- CIS -视黄酯的药物配方

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摘要

Pharmaceutical formulations comprising 9-cis-retinyl esters in a lipid vehicle are described as retinoid replacement therapies for treating retinal degenerations in humans. 展开▼

机译：在脂质载体中包含9- <顺式-视黄基酯的药物制剂被描述为用于治疗人的视网膜变性的类视黄醇替代疗法。展开▼

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公开/公告号WO2011034551A2

专利类型

公开/公告日2011-03-24

原文格式PDF

申请/专利权人 QLT INC.;BOCH RONALD ERWIN;
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申请/专利号WO2009US59126

发明设计人 BOCH RONALD ERWIN;
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申请日2009-09-30

分类号A61K47/44;A61K9;

国家 WO

入库时间 2022-08-21 17:58:41

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1. 含有在脂质媒介物中的9-顺式-视黄酯的药物制剂 [P] . 中国专利： CN102612375B . 2016.01.27

2. 含有在脂质媒介物中的9-顺式-视黄酯的药物制剂 [P] . 中国专利： CN102612375A . 2012-07-25

3. PHARMACEUTICAL FORMULATIONS COMPRISING 9-CIS-RETINYL ESTERS IN A LIPID VEHICLE [P] . AR076184A1 . 2011-05-26

机译：脂质车辆中包含9- CIS -视黄酯的药物配方

4. PHARMACEUTICAL FORMULATIONS COMPRISING 9-CIS-RETINYL ESTERS IN A LIPID VEHICLE [P] . 世界知识产权组织专利： WO2011034551A3 . 2011-12-15

机译：脂质车辆中包含9- CIS -视黄酯的药物配方

5. Pharmaceutical formulations comprising 9-cis-retinyl esters in a lipid vehicle [P] . 美国专利： US10736865B2 . 2020-08-11

机译：在脂质媒介物中包含9-顺-视黄基酯的药物制剂

1. Lipid peroxidation: Its effects on the formulation and use of pharmaceutical emulsions [J] . Ramona Khanum, Haema Thevanayagam 亚洲药物制剂科学(英文) . 2017,第005期

2. New mesogenic Schiff base esters comprising benzothiazole moiety:Synthesis and mesomorphic properties [J] . Sie Tiong Ha, Teck Ming Koh, Guan Yeow Yeap, 中国化学快报（英文版） . 2009,第009期

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5. Colocalization of 11-cis retinyl esters and retinyl ester hydrolase activity in retinal pigment epithelium plasma membrane. [J] . Mata NL, Villazana ET, Tsin AT Investigative ophthalmology & visual science . 1998,第8期

6. Disruption of the 11-cis-Retinol Dehydrogenase Gene Leads to Accumulation of cis-Retinols andcis-Retinyl Esters [J] . Carola A. G. G. Driessen, Huub J. Winkens, Kirstin Hoffmann, Molecular and Cellular Biology . 2000,第12期

7. Disruption of the 11-cis-Retinol Dehydrogenase Gene Leads to Accumulation of cis-Retinols andcis-Retinyl Esters [J] . Carola A. G. G. Driessen, Huub J. Winkens, Kirstin Hoffmann, Molecular and Cellular Biology . 2000,第12期

8. Photoinduced Electron Transfer Processesin 9-cis-Retinyl-C60 Dyad [C] . Mikio Sasaki, Yasuyuki Araki, Mamoru Fujitsuka, International Symposium on Fullerenes, Nanotubes, and Carbon Nanoclusters . 2003

9. Evaluation of the lipid-lowering efficacy of a water dispersible formulation of free sterols versus plant sterol esters in humans consuming a supplemented dairy product. [D] . Amir Shaghaghi, Mandana. 2012

10. Disruption of the 11-cis-Retinol Dehydrogenase Gene Leads to Accumulation of cis-Retinols and cis-Retinyl Esters [O] . Carola A. G. G. Driessen, Huub J. Winkens, Kirstin Hoffmann, 2000

11. Disruption of the 11-cis-Retinol Dehydrogenase Gene Leads to Accumulation of cis-Retinols and cis-Retinyl Esters [O] . Driessen, Carola A. G. G., Winkens, Huub J., Hoffmann, Kirstin, 2000

12. Asymmetric Reduction of Alpha-Keto Esters with Potassium 9-O-(1,2:5,6-Di-O-Isopropylidene-Alpha-D-Glucofuranosyl)-9- Boratabicyclo(3.3.1)Nonane. Chiral Synthesis of Alpha-Hydroxy Esters with Optical Purity Approaching 100% ee [R] . Brown, H. C., Cho, B. T., Park, W. S. 1986

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