首页> 外国专利> DIAGNOSTIC AGENT FOR MESOTHELIOMA, DIAGNOSIS KIT FOR MESOTHELIOMA, AND DIAGNOSIS METHOD FOR MESOTHELIOMA

DIAGNOSTIC AGENT FOR MESOTHELIOMA, DIAGNOSIS KIT FOR MESOTHELIOMA, AND DIAGNOSIS METHOD FOR MESOTHELIOMA

机译:间皮瘤诊断试剂,中皮诊断试剂盒和中皮诊断方法

摘要

The present invention provides a diagnostic agent and the like for mesothelioma which is able to effectively distinguish mesothelioma patients from healthy volunteers, screen mesothelioma patients from among patients with a history of exposure to asbestos, and distinguish mesothelioma patients from patients with other diseases, such as lung cancer, at a higher sensitivity than hitherto reported mesothelioma diagnostic kits or the like. The invention relates to a diagnostic agent for mesothelioma, including, as the active ingredient, an antibody that recognizes an N-terminal side fragment from among fragments formed by leaving 31 kDa secreted Erc/MPF/mesothelin in blood, or in serum that has been separated from blood, at room temperature for at least three hours.
机译:本发明提供了一种用于间皮瘤的诊断剂等,其能够有效地将间皮瘤患者与健康志愿者区分开,从具有石棉接触史的患者中筛选出间皮瘤患者,并将间皮瘤患者与其他疾病如比迄今报道的间皮瘤诊断试剂盒等具有更高的敏感性。本发明涉及间皮瘤的诊断剂,其包括作为活性成分的,通过在血液或血清中残留31kDa的分泌的Erc / MPF /间皮素而形成的片段中识别N末端侧片段的抗体。在室温下与血液分离至少三个小时。

著录项

  • 公开/公告号EP2096168A4

    专利类型

  • 公开/公告日2011-10-26

    原文格式PDF

  • 申请/专利权人 IMMUNO-BIOLOGICAL LABORATORIES CO. LTD.;

    申请/专利号EP20070849806

  • 发明设计人 SEITO TSUTOMU;HINO OKIO;

    申请日2007-12-07

  • 分类号C12N15/09;C07K14/46;C07K16/18;C07K16/30;G01N33/574;

  • 国家 EP

  • 入库时间 2022-08-21 17:57:43

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