PRESOLIDIFIED COMPOSITION AND METHOD FOR IN SITU DELIVERY OF BROAD MOLECULAR WEIGHT RANGE OF CHITOSAN IMPLANTS WITH OR WITHOUT THERAPEUTICS FOR REGENERATIVE MEDICINE AND CARTILAGE REPAIR APPLICATIONS

摘要

The present description relates to a presolidified implant composition, a method for its preparation, and a use of said implant composition for repairing tissue of a patient wherein the implant comprises a blood component, a salt and a polymer which are solidified in a glass or plastic recipient prior to being administered to the patient. The implants are preferably prepared using chitosan as the polymer and may further comprise therapeutics for in vivo release. The presolidified implants are useful for regenerate e medicine and cartilage repair applications.