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ENHANCEMENT OF TRANSGENE EXPRESSION FROM VIRAL-BASED VACCINE VECORS BY EXPRESSION OF SUPPRESSORS OF THE TYPE I INTERFERON RESPONSE
ENHANCEMENT OF TRANSGENE EXPRESSION FROM VIRAL-BASED VACCINE VECORS BY EXPRESSION OF SUPPRESSORS OF THE TYPE I INTERFERON RESPONSE
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机译:通过表达I型干扰素的抑制剂来增强基于病毒的疫苗载体的转基因表达
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摘要
Viral-based vectors are genetically engineered to express inhibitors of the anti-viral immune system (e.g. inhibitors of the type I interferon response) in order to enhance transgene expression. The transgenes may encode antigens or other therapeutic agents.
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