BIO-ANALYSIS USING BALL ENDED INCIDENT AND OUTPUT OPTICAL FIBER AND/OR COPLANAR INCIDENT AND OUTPUT LIGHT GUIDES AND SEPARATION CHANNEL

摘要

A detection optics configuration for bio-analysis, in which the direction of incident radiation (34), the axis of the separation channel (12), and the direction of collection of the output radiation (36) are coplanar at the detection zone (32). In a second invention, the detection configuration incorporates ball -end optical fibers to direct incident radiation at and collection of output radiation from the detection zone (32). The detection optics configuration may be implemented in an improved bio-separation instrument, in particular a capillary electrophoresis instrument.