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A NOVEL WATER SOLUBLE CURCUMIN LOADED NANOPARTICULATE SYSTEM FOR CANCER THERAPY
A NOVEL WATER SOLUBLE CURCUMIN LOADED NANOPARTICULATE SYSTEM FOR CANCER THERAPY
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机译:新型水溶性姜黄素纳米颗粒系统用于癌症治疗
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摘要
The present invention provides a drug delivery system encompassing a water-insoluble drug curcumin for the treatment of cancer. The composition is containing a pharmaceutically acceptable carrier and thus providing a biocompatible drug delivery system. The invention further discloses the nanoparticles composed of glycerol monooleate (GMO), polyvinyl alcohol and pluronic F- 127 and it showed high surface charge (around -32 mV) demonstrating enhanced solubility, stability and bioavailability of entrapped curcumin.
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