CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE

摘要

The invention relates to a carrier and targeting system comprising a siosomal composition for the intracellular delivery and release of a siosome- and/or siosome-liposome-entrapped or encapsulated active substance or therapeutic agent. The invention further relates to the targeted release and delivery of doxorubicin, cis-platin, carbo-platin and/or oxali-platin using said carrier and targeting system. The invention relates to carrier and targeting systems that comprise of charged lipid species, such as cationic or anionic lipids. The invention also relates to a method for preparing such carrier and targeting systems and methods for their administration, particularly in the treatment of cancer.