Physcion-8-O-ß-D-glucopyranoside or physcion of the present invention potently enhances osteoblastic differentiation, mineralization, and bone formation. Therefore, the inventive use of physcion-8-O-ß-D-glucopyranoside or physcion can be advantageously used for enhancing bone formation in a mammal suffering from a bone formation-related disease such as osteoporosis, fracture, periodontal disease, and bone growth disorder.
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