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Pyridine Derivatives, a VFR-2 Receptor and Protein Tyrosine Kinase Inhibitor

机译:吡啶衍生物,VFR-2受体和蛋白质酪氨酸激酶抑制剂

摘要

The invention relates to compounds of general formula (I) wherein W, D, E, G, J, L, R1, R2, R3, R4, R5 and Y are as defined herein, and pharmaceutically acceptable salts, hydrates, or solvates thereof, for usealone or in combination with one or more other pharmaceutically active compoundsin therapy, for treating diseases associated with deregulated angiogenesis, such as cancer and skin and eye diseases.
机译:本发明涉及通式(I)的化合物及其药学上可接受的盐,水合物或溶剂化物,其中W,D,E,G,J,L,R1,R2,R3,R4,R5和Y如本文所定义。单独使用或与一种或多种其他药物活性化合物联合用于治疗,用于治疗与血管新生失调有关的疾病,例如癌症,皮肤和眼部疾病。

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