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SINGLE NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH CORONARY HEART DISEASE AND USES THEREOF
SINGLE NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH CORONARY HEART DISEASE AND USES THEREOF
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机译:与冠心病相关的单核苷酸多态性及其用途
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摘要
The present invention relates to a single nucleotide polymorphism (SNP) associated with coronary artery disease and its use, and more particularly, to a coronary artery disease diagnostic polynucleotide comprising the SNP of the MMP3 gene or a complementary polynucleotide thereof, and a polynucleotide hybridizing thereto. The present invention relates to a polypeptide encoded by the polynucleotide, a microarray and a kit including the polynucleotide, a diagnostic method for coronary artery disease, a method for screening a medicine for treating coronary artery disease, and a pharmaceutical composition for treating coronary artery disease. . The rs679620 polymorphism genotype of the MMP3 gene of the present invention can be usefully used as a marker for diagnosing the genetic susceptibility of coronary artery disease specifically.
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