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Supports and gene arrays for in situ generation of protein arrays, protein arrays obtained therefrom, and methods for manufacture and use thereof
Supports and gene arrays for in situ generation of protein arrays, protein arrays obtained therefrom, and methods for manufacture and use thereof
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机译:用于原位产生蛋白质阵列的支持物和基因阵列,从中获得的蛋白质阵列及其制造和使用方法
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摘要
protein biosynthesis mechanism of the present invention comprises a hydrogel- coated , protein arrays (protein array) of Situ ( in situ ) , and the support for the creation of gene arrays , from which the resulting protein arrays, and the preparation and relates to a method of use, quickly switch the DNA or mRNA of the active protein of the wide array pattern may not only be , since the expressed protein molecules are immobilized in a porous three-dimensional structure of the hydrogel , the sensitivity of the assay using a protein array via an increase in the amount of protein that can be immobilized per unit area can be markedly increased .
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机译:本发明的蛋白质生物合成机制包括水凝胶包被的Situ( ins I>)蛋白质阵列(protein array),以及用于创建基因阵列的支持物,由此产生的蛋白质阵列及其制备方法和使用方法,由于表达的蛋白分子被固定在水凝胶的多孔三维结构中,因此不仅可以快速切换宽阵列模式的活性蛋白的DNA或mRNA,而且使用蛋白质阵列通过增加单位面积固定的蛋白质量的方法的灵敏度可以显着提高。
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