EXTENSION OF TIME TO PROGRESSION OF DISEASE OR LIFETIME OF ONCOLOGIC PATIENTS WITH APPLICATION OF HER DIMERISATION INHIBITORS

摘要

FIELD: medicine.;SUBSTANCE: group of inventions relates to medicine, namely to oncology and may be used to extend the time to progression (TTP) of the disease or duration of life of an oncologic patient. The methods of the invention includes administering of HER dimerisation inhibitor to a patient, which is an antibody binding to domain II of extracellular domain of HER2 and inhibits HER dimerisation 2 or HER heterodimerisation.;EFFECT: use of invention enables to increase survivability in patients due to extending the TTP under the influence of antibody inhibiting the ability of HER2 to form heterodimers with other HER receptors.;23 cl, 1 tbl, 23 dwg, 3 ex