HYPOGLYCEMIC AGENT IN NON-INSULIN-DEPENDENT DIABETES MELLITUS

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: offered is the application of hyaluronidase immobilised by electron-beam synthesis nanotechnology as a hypoglycemic agent effective in non-insulin-dependent diabetes mellitus. The mechanism of action is supposed to be modification of the properties of hyaluronic acid of cell glycocalyx and receptors to insulin It is accompanied by higher ligand sensitivity.;EFFECT: in non-insulin-dependent hyperglycemia, immobilised hyaluronidase caused peripheral blood sugar level decreasing by 41,9 %; insulin concentration has been decreasing statistically significantly.;2 tbl