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APPLICATION OF 2-(2-NITRO-4-TRIFLUORMETHYLBENZOYL)-1,3-CYCLOHEXANDIONE IN TREATMENT OF PARKINSON'S DISEASE
APPLICATION OF 2-(2-NITRO-4-TRIFLUORMETHYLBENZOYL)-1,3-CYCLOHEXANDIONE IN TREATMENT OF PARKINSON'S DISEASE
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机译:2-(2-硝基-4-三氟甲基)-1,3-环己二酮在帕金森病治疗中的应用
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FIELD: medicine, pharmaceutics.;SUBSTANCE: claimed is application of 2-(2-nitro-4-trifluormethylbenzoyl)-1,3-cyclohexandione in production of medication in treatment of neurodegenerative disease, Parkinson's disease, as well as pharmaceutical compositions and sets (versions) of similar purpose, which include said compound.;EFFECT: compound inhibits 4-hydroxypyruvate dioxygenase, reduces time of recovery from catalepsy and increases availability of levodopa or increases dopamine synthesis, i.e. ensures action synergism in treatment of neurodegenerative disease, Parkinson's disease.;23 cl, 4 dwg, 7 tbl, 3 ex
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机译:领域:要求保护的是2-(2-硝基-4-三氟甲基苯甲酰基)-1,3-环己二酮在生产用于治疗神经退行性疾病,帕金森氏病以及药物组合物和药物的药物中的应用(类似的目的的多个版本),包括所述化合物。;作用:该化合物抑制4-羟基丙酮酸双加氧酶,减少从僵直症恢复的时间,并增加左旋多巴的利用率或增加多巴胺的合成,即确保在神经退行性疾病,帕金森氏病的治疗中具有协同作用。; 23 cl,4 dwg,7 tbl,3 ex
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